Manasi Tambe got her first lessons of music from her mother as well as guru Smt. Uttara Kelkar. She has learned classical from Shri. Bhalchandra Tilak and light music from Shri. Ashok Patki.
Manasi Tambe teaches light music to thousands of students from the age of two and half to seventy five years - kids and ladies. While giving music lessons, specially she focusses on perfect breathing techniques, expressions, voice modulation. Also did counselling. She was a champion in 1995-96 in light music for zonal and nationals (Mumbai University). She did anchoring on various channels like D. D Sahyadri, Etv Marathi for Antakshari shows. Also she was singing for Marathi orchestras and 'Zee Alpha dandia', plays like 'Maharashtra Manthan', 'Geet Sungandh', 'Sakhya Sajana' by 'Suyog', 'Goshta Tuzi Mazi'.