Anuradha Rajadhyaksha is a popular actress in the Marathi film and television industry. She has acted in many popular TV serials like Vivahbandhan, Suvasini, Crime Patrol, Reshimgathi. She has also appeared in Aakar, Alguj, Nishpap, Aabhas, Rama O Rama, Kucch Khoya Kucch Paya, Vedh Nishant, Aawaz, Aawart Nanda, Aadhyat Na Madhyat, Manuskicha Mala, Nivdak Chi Vi, Shri Tashi Sau, Manamanachya vyatha, Vad Samvad, Smaran Vismaran, Hip Hip Hurray, Hathkadi, Rajani, Dahashat, Kusum, Kya Kahe, Kahani Ghar Ghar Ki, Kasam Se, Nyay, Aahat, Crime Patrol, Shh..Koi Hai.., Vadalvat, Palkonki Chaav Mein, Chehera, Raja Ki Aayegi Barat, Parivar, Sarathi, Bade Miyan Chote Miyan, Salam Zindagi, Aareccha Kamal aahe, Phiruni Navi Janmen Mi, Mission Dosti.Com, Suvasini, Vivahbandhan, Maaylek, etc.
Anuradha Rajadhyaksha has acted in tele-films like Savli Premachi, Kalat Nakalat, Chi Aani Mul and feature films like Chal Chalein, Pratighat, Saubhagya Kankan, Kunku Lavte Mahercha, Zoom Zam Zombi.
Not just movies, but Anuradha has also portrayed important characters in Marathi plays like Wrong Number, Aandhali Koshimbir, Golmal Sasa Aani Kasav, Vegla Vhaychay Mala, Sakshidar, Tilak Aani Aagarkar, Kalachakra, Priyatama,Vastushant, Sakshidar, Yeta ka Khandalyala, Chal Kahitarich Kay, Prem Kunavarhi Karava, Dev Bappa Sukhi Thev, Sukha Pahata, Varun Saglech Sarakhe, Ya Sukhanno Ya, Bhaubandaki.
TV commercials like Indian Idol, Innova, Tanvi, Suchi, Pomona, Rin Shakti, Ujala, Easy off bang, Acicure, etc. have chosen Anuradha Rajadhyaksha as their model.
She has also been appointed as a Film Censor Committee member by Central Board of Film Certification Government of India. Anuradha Rajadhyaksha is also a guide for Dramatics in Centre for Cultural Resources and Training [CCRT], Government of India.